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Metabolism & Senescence
2-Pack Berberine + Quercetin — Synergistic Formula for Metabolic Health, Cellular Renewal & Healthy Aging (Adults 30+)
Metabolism & Senescence

2-Pack Berberine + Quercetin — Synergistic Formula for Metabolic Health, Cellular Renewal & Healthy Aging (Adults 30+)

60 vegan capsules of Berberine paired with Quercetin capsules, formulated to support AMPK activation, healthy blood sugar balance, inflammatory pathway regulation, and pathways associated with cellular senescence.*

AMPK Activation

Blood Sugar Support

Inflammatory Balance

Senescence Support

⁠Metabolic Health

AMPK Activation

Blood Sugar Support

Inflammatory Balance

Senescence Support

⁠Metabolic Health
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2-Pack Berberine + Quercetin — Synergistic Formula for Metabolic Health, Cellular Renewal & Healthy Aging (Adults 30+)

$71.90
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“Metabolic regulation and inflammatory signaling are deeply interconnected in the biology of aging. Berberine supports metabolic balance through AMPK activation, while Quercetin influences inflammatory and senescence-related pathways. Together they help address two fundamental drivers of age-related metabolic decline.”

 – Dr. Marion Gruffaz, PhD in Molecular Biology, Co-Founder of Solensis

Benefits

Berberine and Quercetin support two complementary biological systems involved in metabolic health and cellular aging.

Berberine is widely studied for its role in activating AMPK, a key regulator of cellular energy and glucose metabolism. Quercetin is a bioactive flavonoid investigated for its influence on inflammatory signaling and cellular communication pathways associated with senescence.

Together, these compounds help support metabolic balance while contributing to cellular resilience in the face of metabolic and inflammatory stressors.

Supplementing with Berberine and Quercetin may help to:

  • Support AMPK activation and metabolic signaling
  • Help maintain healthy blood sugar levels already within a normal range
  • Promote balanced inflammatory pathway activity
  • Support cellular pathways associated with senescence
  • Contribute to long-term metabolic and cellular health*

How To Use It

Take one Berberine capsule and one Quercetin capsule daily with water, preferably with a meal to support absorption.

  • Consistency matters. Daily use supports metabolic balance and healthy inflammatory signaling.
  • Can be used alone or alongside Solensis NMN as part of a structured longevity protocol.
  • Store in a cool, dry place away from direct heat and light.

Who's It For

Our Berberine + Quercetin duo is designed for:

  • Adults 35+ seeking proactive metabolic and cellular aging support
  • Individuals focused on maintaining healthy blood sugar balance
  • Adults 50+ prioritizing metabolic resilience and inflammatory balance
  • Professionals looking to support stable energy and metabolic efficiency
  • Those building a comprehensive longevity protocol with Solensis NMN

Ingredients

  • Berberine HCl – 500 mg per capsule — A well-studied plant-derived alkaloid known for its role in supporting AMPK activation and helping maintain healthy blood sugar levels already within a normal range.
  • Bitter Melon Fruit Extract (10:1) – 100 mg — Traditionally used to support glucose balance and metabolic function.
  • Banaba Leaf Extract (1%) – 25 mg — Contains corosolic acid, studied for its potential role in supporting healthy glucose metabolism.
  • Quercetin (from quercetin dihydrate) – 500 mg per capsule — A naturally occurring flavonoid studied for its role in supporting inflammatory pathway balance and cellular signaling associated with senescence.
  • Bromelain Powder – 100 mg — A proteolytic enzyme derived from pineapple, included to complement inflammatory balance and support absorption.
  • Manufactured in the USA — Produced in cGMP-compliant facilities.
  • Third-Party Tested — Independently verified for identity, purity, and potency.
  • Non-GMO & Vegan Capsules — Plant-based and free from animal-derived ingredients.
  • Other Ingredients: Hydroxypropyl methylcellulose, vegetable magnesium stearate, silicon dioxide.

Third Party Lab Certificate

Every batch undergoes rigorous third-party testing by accredited laboratories to ensure:

✓ Purity Guaranteed
✓ Identity – Confirmed premium ingredient source
✓ Potency – Guaranteed active compound levels in every capsule
✓ Safety – Tested for heavy metals, contaminants, and microbes

We publish our Certificates of Analysis because you deserve to know exactly what you're putting in your body.

View full details

Support healthy blood sugar balance and senescence pathways in as little as 2 weeks.*

Early metabolic signaling support, followed by deeper inflammatory balance and senescence pathway regulation with consistent use.

Week 1 – 2 Early Metabolic Activation*
  • Support for maintaining healthy blood sugar levels
  • Early AMPK pathway activation
  • Initial inflammatory signaling balance
  • Support for metabolic energy regulation
Month 1 – 2 Metabolic & Inflammatory Regulation*
  • More stable glucose metabolism
  • Improved metabolic signaling efficiency
  • Balanced inflammatory pathway activity
  • Support for immune modulation and cellular stress resilience
Month 3+ Long-Term Senescence Pathway Support*
  • Reinforcement of pathways associated with cellular senescence
  • Continued metabolic balance and glucose regulation
  • Support for long-term inflammatory equilibrium
Capsule

How to use

Take one (1) Berberine capsule and one (1) Quercetin capsule daily with water

What our customers are saying

★ ★ ★ ★ ★
BASED ON 498+ TRUSTED REVIEWS
89%
Reported more stable blood sugar levels throughout the day
84%
Noticed improved energy without sharp crashes
76%
Experienced reduced post-meal energy fluctuations
82%
Felt better overall metabolic balance and well-being
★ ★ ★ ★ ★

“I pair this with the berberine for a full senolytic protocol. The quercetin handles clearing out the zombie cells while the berberine supports autophagy. Together they've made a noticeable difference in my energy, joint comfort, and how I feel when I wake up in the morning. No more dragging myself out of bed.”

Maria E.

VERIFIED BUYER ✔

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0

YEARS OF RESEARCH

Investigating Berberine and Quercetin in metabolic regulation and cellular aging science.

0

HUMAN CLINICAL TRIALS

Evaluating these compounds in metabolic, inflammatory, and cardiometabolic research.

0

SCIENTIFIC PUBLICATIONS

Exploring AMPK signaling, inflammatory pathways, and senescence biology.

0

SATISFIED CUSTOMERS

Who trust Solensis for science-driven longevity support.

Beautiful woman

LED BY SCIENCE. NOT HYPE.

The metabolic & senescence science

Metabolic regulation and inflammatory signaling are two key biological systems involved in healthy aging. Berberine has been extensively studied for activating AMPK, a central metabolic regulator that influences glucose metabolism, lipid balance, and cellular energy production. Quercetin is a bioactive plant flavonoid investigated for its role in inflammatory signaling and senescence-related cellular pathways, helping support balanced immune and cellular communication. By supporting both metabolic regulation and inflammatory balance, these compounds contribute to cellular resilience against metabolic stress and age-related signaling changes. Backed by decades of research and thousands of scientific publications, Berberine and Quercetin remain two of the most studied plant-derived compounds in metabolic and longevity science.

Supports AMPK metabolic pathways

Promotes healthy blood sugar balance

Contributes to inflammatory signaling balance

Supports pathways associated with cellular senescence

References
1. Turner N., et al. (2008). Berberine and its metabolic effects: AMPK activation, improvement of glucose tolerance and lipid regulation in insulin-resistant states. Diabetes, 57(5), 1414–1418. 2. Ye Y., et al. (2021). The effect of berberine on metabolic profiles in type 2 diabetic patients: a systematic review and meta-analysis of randomized controlled trials. Oxidative Medicine and Cellular Longevity. 3. Kirkland J.L. & Tchkonia T. (2019). Senolytics decrease senescent cells in humans: preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease. EBioMedicine, 47, 446–456. 4. Islam M.T., et al. (2023). Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation and ameliorate metabolic function in old age. Aging Cell, 22(2), e13767.
The metabolic & senescence science
Founder portrait
OUR FOUNDER

A leading expert in cellular biology at the origin of Solensis.

Solensis was co-founded by Dr. Marion Gruffaz, PhD in Molecular Biology and former USC researcher.

Driven by years of scientific research, she created Solensis to bridge the gap between molecular science and real-world longevity solutions. Every formulation is guided by peer-reviewed evidence, tested for purity, and designed for measurable results.

Learn more about Solensis

6,000+ customers. 4.8★ average rating

These are verified customers who experienced positive health outcomes through consistent product use.
Jenithaa S.
★ ★ ★ ★ ★

“Ever since starting I feel mentally alert and my energy level is sky rocketing. My body feels and looks younger.”

Jenithaa S.

VERIFIED BUYER ✔

Morris A.
★ ★ ★ ★ ★

“I saw an improvement in my energy level and mental clarity within a few days after I start taking this NMN from Solensis.”

Morris A.

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Leah M.
★ ★ ★ ★ ★

“This is my first time purchasing from Solensis and I’m very impressed with the quality of their supplements.”

Leah M.

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Monica D.
★ ★ ★ ★ ★

“It made me feel better and more energetic after a week of use. I am 100% addicted to this brand.”

Monica D.

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Amy D.
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“This is my first time purchasing from Solensis and I’m very impressed with the quality of their supplements.”

Amy D.

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Marina D.
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“I'm really happy with it and I highly recommend it!”

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“I love the Innovage Night Cream! After just a few weeks, my skin feels firmer, softer, and looks noticeably smoother.”

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Oxana F.
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“My general health has improved, and I will be a repeating customer. My overall health as well as my ability to sleep improved. Fantastic product!”

Oxana F.

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Jason G.
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“I feel this NMN makes me feel much more energetic. Highly recommended.”

Jason G.

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30-Day Feel the Difference Guarantee

Experience it for 30 days. If you don’t notice meaningful improvements in energy and well-being, we’ll refund your purchase in full.

Feel Better, Consistently

Designed for everyday support

See Real Results

Formulated for noticeable impact

Trust What You Use

Reliable quality, every time

Rigorous testing that sets a higher standard.

Third party testing and strict quality controls, so what’s on the label is exactly what’s in every scoop.

  • Non-GMO & Vegan
  • Purity Guaranteed
  • GMP Certified
  • Scientifically backed
  • Third-party Tested
  • Made in the USA

Synergistic longevity bundles

SAVE UP TO 20% WITH BUNDLES
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Each Solensis bundle is designed to support a different axis of healthy aging — from NAD⁺ and mitochondrial energy to antioxidant defense and skin repair.

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Questions? We're here to help.

Find answers to the most common questions about combining Berberine and Quercetin.

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